Metabolic Concerns in Polycystic Ovary Syndrome: Innovative Approaches to Medical Management

Background Among the infertility disorders, polycystic ovary syndrome (PCOS) is one of the most common, affecting approximately 4 million women in the U.S. and more than 100 million women worldwide.1 PCOS is characterized by both reproductive and metabolic dysfunctions with familial clustering.2 From a reproductive perspective, PCOS is a heterogeneous syndrome characterized by hyperandrogenism (diagnosed clinically/biochemically) with oligomenorrhea and chronic anovulation in the absence of specific ovarian, adrenal and pituitary gland diseases.3-5